Amylyx Pharmaceuticals, Inc. (AMLX) Short Interest
AMLX Short Interest & Days to Cover
Amylyx Pharmaceuticals, Inc. (AMLX) currently has 13.4M shares short as of the Jul 31, 2026 settlement date, or about 6.8 days to cover at current trading volume. That is higher than 73% of the 110 readings on record since Jan 14, 2022, on a days-to-cover basis. Shares short have risen for 1 straight reporting period. Looking at recent periods where short interest increased, the stock is now averaging +117.6% since those additions, recent short sellers are broadly underwater on that basis.
As of the Jul 31, 2026 settlement date, short interest is reported roughly every two weeks, not in real time.
Days to cover, compared against every biweekly reading on record for this stock specifically, not the market as a whole.
Short interest moving alone does not say much, what matters is whether it is moving with or against the price. Each period below compares the change in short interest to the stock's move over the same window.
| Settlement Date | SI Change | Read |
|---|---|---|
| Jul 31, 2026 | +9.2% | New bearish bets despite strength |
| Jul 15, 2026 | -14.7% | Covering into weakness |
| Jun 30, 2026 | +9.7% | New bearish bets despite strength |
| Jun 15, 2026 | -12.3% | Covering into strength |
| May 29, 2026 | +3.1% | New bearish bets despite strength |
| May 15, 2026 | -2.0% | — |
| Apr 30, 2026 | -0.2% | — |
| Apr 15, 2026 | +4.2% | New bearish bets despite strength |
Comparing the stock's price at each recent short-interest-increase to where it trades today. An estimate based on settlement-date prices, not any individual short seller's real entry.
| Build Date | Price Then | Return Since |
|---|---|---|
| Feb 13, 2026 | $14.12 | +146.0% |
| Mar 31, 2026 | $13.90 | +149.9% |
| Apr 15, 2026 | $17.12 | +102.9% |
| May 29, 2026 | $14.35 | +142.1% |
| Jun 30, 2026 | $17.96 | +93.4% |
| Jul 31, 2026 | $20.31 | +71.0% |
The 28 periods where short interest was in the top quarter of AMLX's own history on record (+7.29% or higher), and what followed.
| Forward Window | Avg Return | Win Rate |
|---|---|---|
| 3 months | -4.6% | 33% (n=24) |
| 6 months | -23.8% | 28% (n=18) |
| 12 months | -86.9% | 0% (n=13) |
A historical pattern in AMLX's own data, not a prediction.
Every biweekly settlement reading on record, most recent first. Page 1 of 3.
| Settlement Date | Shares Short | Days to Cover | Avg Daily Volume | Change |
|---|---|---|---|---|
| Jul 31, 2026 | 13.4M | 6.8 | 2.0M | +9.2% |
| Jul 15, 2026 | 12.3M | 8.9 | 1.4M | -14.7% |
| Jun 30, 2026 | 14.4M | 10.6 | 1.4M | +9.7% |
| Jun 15, 2026 | 13.1M | 11.1 | 1.2M | -12.3% |
| May 29, 2026 | 15.0M | 13.7 | 1.1M | +3.1% |
| May 15, 2026 | 14.5M | 13.4 | 1.1M | -2.0% |
| Apr 30, 2026 | 14.8M | 14.6 | 1.0M | -0.2% |
| Apr 15, 2026 | 14.8M | 12.4 | 1.2M | +4.2% |
| Mar 31, 2026 | 14.2M | 11.1 | 1.3M | +2.7% |
| Mar 13, 2026 | 13.9M | 9.7 | 1.4M | -4.4% |
| Feb 27, 2026 | 14.5M | 10.3 | 1.4M | +1.3% |
| Feb 13, 2026 | 14.3M | 9.4 | 1.5M | +4.1% |
| Jan 30, 2026 | 13.8M | 8.4 | 1.6M | +2.3% |
| Jan 15, 2026 | 13.4M | 8.7 | 1.6M | -1.5% |
| Dec 31, 2025 | 13.6M | 8.6 | 1.6M | +13.0% |
| Dec 15, 2025 | 12.1M | 7.5 | 1.6M | +3.9% |
| Nov 28, 2025 | 11.6M | 6.5 | 1.8M | -2.4% |
| Nov 14, 2025 | 11.9M | 6.6 | 1.8M | +14.0% |
| Oct 31, 2025 | 10.4M | 6.2 | 1.7M | +8.6% |
| Oct 15, 2025 | 9.6M | 5.9 | 1.6M | -4.5% |
| Sep 30, 2025 | 10.1M | 6.2 | 1.6M | +14.8% |
| Sep 15, 2025 | 8.8M | 5.1 | 1.7M | +4.3% |
| Aug 29, 2025 | 8.4M | 5.6 | 1.5M | +13.2% |
| Aug 15, 2025 | 7.4M | 5.2 | 1.4M | +3.3% |
| Jul 31, 2025 | 7.2M | 4.9 | 1.5M | -3.7% |
| Jul 15, 2025 | 7.5M | 5.1 | 1.5M | +12.8% |
| Jun 30, 2025 | 6.6M | 5.4 | 1.2M | +63.9% |
| Jun 13, 2025 | 4.0M | 4.5 | 896K | -2.2% |
| May 30, 2025 | 4.1M | 4.4 | 934K | -16.9% |
| May 15, 2025 | 5.0M | 5.8 | 862K | +18.3% |
| Apr 30, 2025 | 4.2M | 5.2 | 807K | -2.6% |
| Apr 15, 2025 | 4.3M | 5.1 | 840K | +14.0% |
| Mar 31, 2025 | 3.8M | 4.5 | 831K | +0.8% |
| Mar 14, 2025 | 3.8M | 4.4 | 849K | +2.7% |
| Feb 28, 2025 | 3.6M | 4.6 | 786K | +8.0% |
| Feb 14, 2025 | 3.4M | 3.7 | 908K | +30.5% |
| Jan 31, 2025 | 2.6M | 2.5 | 1.1M | +4.4% |
| Jan 15, 2025 | 2.5M | 2.0 | 1.3M | +27.8% |
| Dec 31, 2024 | 1.9M | 1.5 | 1.3M | +23.6% |
| Dec 13, 2024 | 1.6M | 1.1 | 1.4M | +8.3% |
| Nov 29, 2024 | 1.4M | 1.0 | 1.5M | -5.2% |
| Nov 15, 2024 | 1.5M | 1.1 | 1.4M | +18.6% |
| Oct 31, 2024 | 1.3M | 1.0 | 1.3M | +27.7% |
| Oct 15, 2024 | 1.0M | 0.9 | 1.1M | -21.1% |
| Sep 30, 2024 | 1.3M | 0.9 | 1.4M | +1.6% |
| Sep 13, 2024 | 1.3M | 0.8 | 1.6M | -15.4% |
| Aug 30, 2024 | 1.5M | 0.9 | 1.6M | -24.4% |
| Aug 15, 2024 | 2.0M | 1.2 | 1.7M | +5.9% |
| Jul 31, 2024 | 1.9M | 1.1 | 1.8M | -50.8% |
| Jul 15, 2024 | 3.8M | 1.9 | 2.0M | -17.3% |
What is AMLX's current short interest?
Amylyx Pharmaceuticals, Inc. has 13.4M shares sold short as of Jul 31, 2026. Days to cover is 6.8.
Is AMLX's short interest high or low right now?
On a days-to-cover basis, current short interest is higher than 73% of the 110 biweekly readings on record, spanning Jan 14, 2022 to Jul 31, 2026. The historical average days to cover is 5.2, and the highest on record is 14.6 days, on Apr 30, 2026.
Is short interest in AMLX rising or falling?
Shares short have risen for 1 consecutive reporting period.
Are short sellers in AMLX currently winning or losing?
Looking at the 6 most recent periods where short interest increased, the stock has averaged +117.6% since those additions, with price now below the entry level in 0% of those cases. This is an estimate based on the price at each settlement date, not a precise tracking of any individual short seller's actual entry.
What has historically happened after AMLX's short interest was this high?
In the 28 periods where days to cover was in the top quarter of this ticker's own history (7.3 days or higher), the stock averaged -23.8% over the following 6 months (positive 28% of the time, n=18). This is a historical pattern, not a prediction.