Amylyx Pharmaceuticals, Inc. (AMLX) Insider Transactions
AMLX Insider Buying & Selling Activity
Between Aug 12, 2025 and Jul 10, 2026, 6 insiders at Amylyx Pharmaceuticals, Inc. (AMLX) reported 29 transactions on record: 2 purchases and 27 sales. In total, insiders bought $152.2K and sold $7.92M, a net selling position of $7.77M. 5 insiders also sold within a 30-day window around Mar 2, 2026.
Multiple insiders trading the same direction in a short window is generally read as a stronger signal than any single trade alone.
| Date | Insider | Role | Type | Shares | Value |
|---|---|---|---|---|---|
| Jan 15, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 136.2K | $1.85M |
| Jan 15, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sale | 136.2K | $1.85M |
| Sep 30, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sale | 30.0K | $431.0K |
| Sep 30, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 29.9K | $429.5K |
| Mar 2, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 29.3K | $424.1K |
Every insider with activity on record, most recently active first.
| Insider | Role | Last Activity | Date | Latest Known Holding |
|---|---|---|---|---|
| Mazzariello Gina | Chief Legal Officer | Sale | Jul 10, 2026 | 179.1K |
| Firestone Karen | Director | Purchase | May 21, 2026 | 66.9K |
| Klee Justin B. | Co-Chief Executive Officer | Sale | Mar 2, 2026 | 3.33M |
| FRATES JAMES M | Chief Financial Officer | Sale | Mar 2, 2026 | 165.6K |
| Cohen Joshua B | Co-Chief Executive Officer | Sale | Mar 2, 2026 | 3.33M |
| Bedrosian Camille L | Chief Medical Officer | Sale | Mar 2, 2026 | 169.3K |
Every purchase and sale on record, deduplicated. "52w range" shows where that price sat in the trailing year at the time, and "Since" shows the paper return from that price to today.
| Date | Insider | Role | Type | Shares | Price | Value | 52w Range | Since |
|---|---|---|---|---|---|---|---|---|
| Jul 10, 2026 | Mazzariello Gina | Chief Legal Officer | Sale | 15.0K | $17.61 | $264.1K | 92% | +97.3% |
| Jul 9, 2026 | Mazzariello Gina | Chief Legal Officer | Sale | 15.0K | $18.32 | $274.7K | 97% | +89.6% |
| May 21, 2026 | Firestone Karen | Director | Purchase | 3.8K | $13.51 | $51.3K | 68% | +157.1% |
| Mar 2, 2026 | Mazzariello Gina | Chief Legal Officer | Sale | 6.8K | $14.52 | $99.4K | 88% | +139.3% |
| Mar 2, 2026 | FRATES JAMES M | Chief Financial Officer | Sale | 7.9K | $14.52 | $114.9K | 88% | +139.3% |
| Mar 2, 2026 | Bedrosian Camille L | Chief Medical Officer | Sale | 6.5K | $14.58 | $94.2K | 88% | +138.3% |
| Mar 2, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 29.3K | $14.48 | $424.1K | 88% | +139.9% |
| Mar 2, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sale | 29.3K | $14.47 | $423.8K | 88% | +140.1% |
| Feb 23, 2026 | Mazzariello Gina | Chief Legal Officer | Sale | 3.4K | $14.14 | $48.4K | 78% | +145.7% |
| Feb 2, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sale | 15.5K | $14.69 | $227.6K | 84% | +136.5% |
| Feb 2, 2026 | Mazzariello Gina | Chief Legal Officer | Sale | 3.4K | $14.65 | $50.5K | 84% | +137.1% |
| Feb 2, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 15.5K | $14.68 | $227.6K | 84% | +136.6% |
| Feb 2, 2026 | FRATES JAMES M | Chief Financial Officer | Sale | 3.6K | $14.65 | $52.1K | 84% | +137.1% |
| Jan 16, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sale | 2.0K | $13.89 | $27.7K | 88% | +150.1% |
| Jan 16, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 2.0K | $13.83 | $27.3K | 88% | +151.2% |
| Jan 15, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sale | 136.2K | $13.58 | $1.85M | 82% | +155.8% |
| Jan 15, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 136.2K | $13.59 | $1.85M | 82% | +155.6% |
| Jan 6, 2026 | Klee Justin B. | Co-Chief Executive Officer | Sale | 7.7K | $11.09 | $85.6K | 66% | +213.3% |
| Jan 6, 2026 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 7.7K | $11.09 | $85.6K | 66% | +213.3% |
| Jan 6, 2026 | FRATES JAMES M | Chief Financial Officer | Sale | 3.3K | $11.11 | $37.0K | 66% | +212.7% |
| Dec 23, 2025 | Firestone Karen | Director | Purchase | 8.1K | $12.45 | $100.8K | 73% | +179.0% |
| Dec 1, 2025 | Bedrosian Camille L | Chief Medical Officer | Sale | 6.6K | $14.35 | $94.4K | 88% | +142.1% |
| Sep 30, 2025 | Bedrosian Camille L | Chief Medical Officer | Sale | 12.0K | $14.58 | $175.5K | 89% | +138.3% |
| Sep 30, 2025 | Cohen Joshua B | Co-Chief Executive Officer | Sale | 29.9K | $14.35 | $429.5K | 89% | +142.1% |
| Sep 30, 2025 | FRATES JAMES M | Chief Financial Officer | Sale | 10.6K | $14.65 | $154.7K | 89% | +137.1% |
| Sep 30, 2025 | Mazzariello Gina | Chief Legal Officer | Sale | 8.8K | $14.58 | $128.7K | 89% | +138.3% |
| Sep 30, 2025 | Klee Justin B. | Co-Chief Executive Officer | Sale | 30.0K | $14.38 | $431.0K | 89% | +141.6% |
| Aug 13, 2025 | Mazzariello Gina | Chief Legal Officer | Sale | 15.0K | $8.34 | $125.0K | 98% | +316.5% |
| Aug 12, 2025 | Mazzariello Gina | Chief Legal Officer | Sale | 15.0K | $8.07 | $121.1K | 97% | +330.5% |
52w range and paper return are only computed for transactions with a date that lines up with price history on record.
Are insiders buying or selling AMLX stock?
On record between Aug 12, 2025 and Jul 10, 2026, Amylyx Pharmaceuticals, Inc. insiders made 2 purchases ($152.2K) and 27 sales ($7.92M), a net selling position of $7.77M.
Has there been cluster buying or selling at AMLX?
No buying clusters (2+ insiders within 30 days) on record. 5 insiders sold within 30 days around Sep 30, 2025; 4 insiders sold within 30 days around Feb 2, 2026; 5 insiders sold within 30 days around Mar 2, 2026.
What is the largest recent insider transaction at AMLX?
The largest transaction on record is Cohen Joshua B (Co-Chief Executive Officer), a sale of $1.85M on Jan 15, 2026.
Does a 10b5-1 automatic trading plan explain AMLX's insider sales?
This data does not indicate whether a given sale was part of a pre-scheduled Rule 10b5-1 plan, that detail is not captured in the transaction data available here.